Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 3/20 | 0.33 |
| ▸ | CPT2 | P23786 | 2/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560588 | 0.73 | KDM4E (0.33) | ALDH1A1KDM4ECYP2D6TSHRCYP2C19 | |
| SCHEMBL670654 | 0.72 | HIF1A (0.43) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL5691059 | 0.69 | ALDH1A1 (0.41) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL26361 | 0.67 | ALDH1A1 (0.45) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL10589741 | 0.67 | — | — | |
| SCHEMBL16374685 | 0.67 | ALDH1A1 (0.45) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Ammonia Solution, Strong SCHEMBL10589727 | 0.67 | ALDH1A1 (0.39) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL9771853 | 0.67 | ALDH1A1 (0.40) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL7148379 | 0.67 | ALDH1A1 (0.40) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL7148369 | 0.67 | ALDH1A1 (0.40) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103293145-B | Chemical luminous reagent | 赫利森（厦门）生物科技有限公司 | 2016-08-10 | — | — | CN | disclosed |
| US-20160222379-A1 | USE OF MULTIPLE RECOMBINATION SITES WITH UNIQUE SPECIFICITY IN COMBINATIONAL CLONING | INVITROGEN CORPORATION | 2016-08-04 | — | — | US | disclosed |
| US-20140296093-A1 | USE OF MULTIPLE RECOMBINATION SITES WITH UNIQUE SPECIFICITY IN COMBINATIONAL CLONING | Life Technologies Corporation (US) | 2014-10-02 | — | — | US | disclosed |
| US-20140051843-A1 | METHODS AND COMPOSITIONS FOR DETECTING PROMOTER ACTIVITY AND EXPRESSING FUSION PROTEINS | Life Technologies Corporation (US) | 2014-02-20 | — | — | US | disclosed |
| CN-103293145-A | Chemical luminous reagent | HELIOSENSE BIOTECHNOLOGIES INC | 2013-09-11 | — | — | CN | disclosed |
| US-20120183999-A1 | USE OF MULTIPLE RECOMBINATION SITES WITH UNIQUE SPECIFICITY IN COMBINATIONAL CLONING | Life Technologies Corporation (US) | 2012-07-19 | — | — | US | disclosed |
| US-20110275541-A1 | USE OF MULTIPLE RECOMBINATION SITES WITH UNIQUE SPECIFICITY IN COMBINATIONAL CLONING | INVITROGEN CORPORATION (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110269120-A1 | METHODS AND COMPOSITIONS FOR DETECTING PROMOTER ACTIVITY AND EXPRESSING FUSIONPROTEINS | Life Technologies Corporation (US) | 2011-11-03 | — | — | US | disclosed |
| US-20090176975-A1 | METHODS AND COMPOSITIONS FOR DETECTING PROMOTER ACTIVITY AND EXPRESSING FUSION PROTEINS | INVITROGEN CORPORATION (US) | 2009-07-09 | — | — | US | disclosed |
| US-7351578-B2 | Use of multiple recombination sites with unique specificity in recombinational cloning | INVITROGEN CORP. (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1644538-A4 | METHODS AND COMPOSITIONS FOR DETECTING PROMOTER ACTIVITY AND EXPRESSING FUSION PROTEINS | INVITROGEN CORP (US) | 2006-11-08 | — | — | EP | disclosed |
| EP-1644538-A2 | METHODS AND COMPOSITIONS FOR DETECTING PROMOTER ACTIVITY AND EXPRESSING FUSION PROTEINS | INVITROGEN CORPORATION (US) | 2006-04-12 | — | — | EP | disclosed |
| US-20050095615-A1 | Methods and compositions for detecting promoter activity and expressing fusion proteins | Life Technologies Corporation | 2005-05-05 | — | — | US | disclosed |
| WO-2005028615-A2 | METHODS AND COMPOSITIONS FOR DETECTING PROMOTER ACTIVITY AND EXPRESSING FUSION PROTEINS | INVITROGEN CORPORATION (US) | 2005-03-31 | — | — | WO | disclosed |
| US-20040229229-A1 | Microarray comprising two or more immobilized vectors for use as replication and gene transfer tools; simultaneous cloning of two or more nucleotide sequences | INVITROGEN CORPORATION | 2004-11-18 | — | — | US | disclosed |
| US-20020192736-A1 | Assay of peroxidase activity | PIERCE CHEMICAL COMPANY | 2002-12-19 | — | — | US | disclosed |
| EP-0898620-B1 | ASSAY OF PEROXIDASE ACTIVITY | PIERCE CHEMICAL CO (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6432662-B1 | SOLUTION OF CHEMILUMINESCENT CYCLIC DIACYLHYDRAZIDE, AT LEAST ONE AZINE ENHANCER AND AT LEAST ONE OXIDIZING AGENT | PIERCE CHEMICAL COMPANY | 2002-08-13 | — | — | US | disclosed |
| EP-0898620-A1 | ASSAY OF PEROXIDASE ACTIVITY | PIERCE CHEMICAL COMPANY (US) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997039142-A1 | ASSAY OF PEROXIDASE ACTIVITY | PIERCE CHEMICAL COMPANY (US) | 1997-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051843-A1 | METHODS AND COMPOSITIONS FOR DETECTING PROMOTER ACTIVITY AND EXPRESSING FUSION PROTEINS | RNGTT, CPSF6, NUDT21 | ALDH1A1 4182/4885HMGCR 4687/4885CHRM1 4840/4885 |
| US-20110269120-A1 | METHODS AND COMPOSITIONS FOR DETECTING PROMOTER ACTIVITY AND EXPRESSING FUSIONPROTEINS | RNGTT, CPSF6, NUDT21 | ALDH1A1 4075/4885HMGCR 4627/4885CHRM1 4829/4885 |
| US-20090176975-A1 | METHODS AND COMPOSITIONS FOR DETECTING PROMOTER ACTIVITY AND EXPRESSING FUSION PROTEINS | RNGTT, CPSF6, NUDT21 | ALDH1A1 4182/4885HMGCR 4687/4885CHRM1 4840/4885 |
| US-20050095615-A1 | Methods and compositions for detecting promoter activity and expressing fusion proteins | RNGTT, CPSF6, NUDT21 | ALDH1A1 4182/4885HMGCR 4687/4885CHRM1 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.