Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.60 |
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015796 | 0.88 | TAAR1 (0.54) | AGXTKIF11MAOBTAAR1SIGMAR1 | |
| SCHEMBL257786 | 0.86 | AGXT (0.64) | AGXTKIF11MAOBCASRTAAR1 | |
| SCHEMBL12158551 | 0.84 | FFAR1 (0.58) | AGXTMAOBFFAR1 | |
| SCHEMBL24005570 | 0.84 | CTSS (0.50) | AGXTCTSSCTSK | |
| SCHEMBL18014707 | 0.83 | AGXT (0.60) | AGXTKIF11MAOBCASRPTPN5 | |
| SCHEMBL19567187 | 0.83 | MAOB (0.69) | AGXTKIF11MAOBTAAR1PTPN5 | |
| SCHEMBL2652456 | 0.83 | AGXT (0.60) | AGXTKIF11MAOBCASRTAAR1 | |
| SCHEMBL27962427 | 0.83 | AGXT (0.60) | AGXTKIF11MAOBCASRTAAR1 | |
| SCHEMBL9809579 | 0.82 | MAOB (0.63) | KIF11MAOBTAAR1CTSSCTSK | |
| SCHEMBL15238584 | 0.82 | MCL1 (0.49) | MAOBTAAR1MAPTFFAR1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249111-A1 | MULTI-RING COMPOUNDS AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249111-A1 | MULTI-RING COMPOUNDS AND USES THEREOF | TP53, BCOR, HPGDS | AGXT 1644/4885KIF11 4113/4885MAOB 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.