Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469571 | 0.83 | CHRM5 (0.45) | CHRM5CHRM3KCNH2OPRD1NPY1R | |
| SCHEMBL2472642 | 0.79 | KMT2A (0.52) | CHRM5CHRM3KCNH2OPRD1MAPT | |
| SCHEMBL2470804 | 0.77 | TSHR (0.53) | CHRM5CHRM3KCNH2OPRD1MAPT | |
| SCHEMBL2469507 | 0.77 | USP2 (0.53) | CHRM5CHRM3KCNH2OPRD1ALDH1A1 | |
| SCHEMBL2472072 | 0.77 | ALDH1A1 (0.48) | CHRM5CHRM3KCNH2OPRD1MAPT | |
| SCHEMBL2472775 | 0.76 | KMT2A (0.48) | CHRM5CHRM3KCNH2OPRD1MAPT | |
| SCHEMBL2472772 | 0.76 | KMT2A (0.48) | CHRM5CHRM3KCNH2OPRD1MAPT | |
| SCHEMBL2860469 | 0.75 | ALDH1A1 (0.56) | CHRM5CHRM3MAPTALDH1A1KMT2A | |
| SCHEMBL2468936 | 0.74 | ALDH1A1 (0.58) | CHRM5CHRM3KCNH2OPRD1MAPT | |
| SCHEMBL2467331 | 0.74 | TAS1R3 (0.48) | CHRM5CHRM3KCNH2OPRD1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2228065-A2 | Heterocyclo inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2010-09-15 | — | — | EP | disclosed |