Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305342 | 0.86 | AKR1C3 (0.59) | AKR1C3KMT2ATSHRGAAMAPT | |
| SCHEMBL188296 | 0.85 | MEN1 (0.65) | KMT2AMEN1SMN1; SMN2TSHRGAA | |
| SCHEMBL29447165 | 0.82 | AKR1C3 (0.85) | AKR1C3KMT2AMEN1TSHRGAA | |
| SCHEMBL700595 | 0.82 | AKR1C3 (0.85) | AKR1C3KMT2AMEN1TSHRGAA | |
| SCHEMBL3309083 | 0.82 | AKR1C3 (0.53) | AKR1C3SMN1; SMN2TSHRGAAMAPT | |
| SCHEMBL1018643 | 0.81 | ALDH1A1 (0.64) | AKR1C3KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL18919366 | 0.81 | AKR1C3 (0.57) | AKR1C3KMT2ATSHRGAAMAPT | |
| SCHEMBL28883310 | 0.80 | AKR1C3 (0.81) | AKR1C3KMT2AMEN1SMN1; SMN2GAA | |
| Fluoride SCHEMBL28319246 | 0.80 | AKR1C3 (0.81) | AKR1C3KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL13159280 | 0.79 | HPGD (0.69) | AKR1C3KMT2AMEN1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222454-A1 | DEGRADATION ACCELERATOR FOR POLYMERS AND POLYMER ARTICLE COMPRISING IT | CIBA CORPORATION (US) | 2010-09-02 | — | — | US | disclosed |