SCHEMBL3305342

SCHEMBL3305342

CN(O)C(=O)c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.59
TSHR P16473 1/20 0.51
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
ALDH1A1 P00352 3/20 0.48
ATM Q13315 2/20 0.47
CDC25B P30305 1/20 0.47
HSP90AA1 P07900 1/20 0.46
PKM P14618 1/20 0.46
CCR6 P51684 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TLR9 Q9NR96 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
POLB P06746 1/20 0.46
NR4A1 P22736 1/20 0.46
KMT2A Q03164 1/20 0.45
MYC P01106 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13183116 0.86 AKR1C3 (0.61) AKR1C3TSHRGAAMAPTHPGD
SCHEMBL3280428 0.85 TP53 (0.50) TSHRGAAMAPTHPGDALDH1A1
SCHEMBL700595 0.81 AKR1C3 (0.85) AKR1C3TSHRGAAMAPTALDH1A1
SCHEMBL29447165 0.81 AKR1C3 (0.85) AKR1C3TSHRGAAMAPTALDH1A1
SCHEMBL3309083 0.80 AKR1C3 (0.53) AKR1C3TSHRGAAMAPTHPGD
SCHEMBL3305633 0.80 HPGD (0.62) MAPTHPGDNPC1RAB9AALDH1A1
SCHEMBL18919366 0.79 AKR1C3 (0.57) AKR1C3TSHRGAAMAPTHPGD
SCHEMBL125680 0.79 HSP90AA1 (0.54) TSHRHPGDNPC1RAB9AALDH1A1
Fluoride SCHEMBL28319246 0.79 AKR1C3 (0.81) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL28883310 0.79 AKR1C3 (0.81) AKR1C3GAAMAPTALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100093883-A1 Hydroxamic Esters as Photoinitiators LAMBERTI SPA (IT) 2010-04-15 US disclosed
CN-101646564-A Hydroxamates as photoinitiators LAMBERTI SPA IT 2010-02-10 CN disclosed
EP-2121323-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS Lamberti Spa (IT) 2009-11-25 EP disclosed
WO-2008104436-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS LAMBERTI SPA (IT) 2008-09-04 WO disclosed