SCHEMBL13183261

SCHEMBL13183261

COC(=O)CC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.39
GAA P10253 3/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
TP53 P04637 1/20 0.36
TSHR P16473 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.33
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ATM Q13315 1/20 0.33
MEN1 O00255 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTT P42858 1/20 0.33
GLA P06280 1/20 0.32
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2618714 0.92 MGLL (0.34) BRD4KMT2AALDH1A1HPGDATM
SCHEMBL2454952 0.86 TSHR (0.50) BRD4GAATSHRSMN1; SMN2KMT2A
SCHEMBL6033533 0.84 MGAM (0.43) BRD4GAAMGAMSIMGAM2
SCHEMBL14141438 0.83 TSHR (0.54) BRD4TSHRSMN1; SMN2KMT2AALDH1A1
SCHEMBL264567 0.83 TSHR (0.48) TSHRSMN1; SMN2KMT2AALDH1A1HPGD
SCHEMBL24564946 0.83 SMN1; SMN2 (0.40) BRD4GAAMGAMSIMGAM2
SCHEMBL13160465 0.83 KMT2A (0.32) BRD4KMT2AATMMGLL
SCHEMBL19463301 0.82 TSHR (0.47) TSHRSMN1; SMN2KMT2AALDH1A1HPGD
SCHEMBL29044559 0.82 TSHR (0.47) TSHRSMN1; SMN2KMT2AALDH1A1HPGD
SCHEMBL905407 0.82 TSHR (0.47) TSHRSMN1; SMN2KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034661-B2 Method for producing molecule immobilizing substrate, and molecule immobilizing substrate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-19 US disclosed
US-20140249076-A1 AMYLIN-CALCITONIN CHIMERIC PEPTIDES CONJUGATED TO DURATION ENHANCING MOIETIES ASTRAZENECA PHARMACEUTICALS LP 2014-09-04 US disclosed
US-20100233827-A1 METHOD FOR PRODUCING MOLECULE IMMOBILIZING SUBSTRATE, AND MOLECULE IMMOBILIZING SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140249076-A1 AMYLIN-CALCITONIN CHIMERIC PEPTIDES CONJUGATED TO DURATION ENHANCING MOIETIES IAPP, GIPR, VIP BRD4 4533/4885GAA 437/4885MGAM 1208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.