Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264567 | 0.93 | TSHR (0.48) | TSHRALDH1A1LMNAKMT2AHTT | |
| SCHEMBL14141438 | 0.93 | TSHR (0.54) | TSHRALDH1A1LMNAKMT2AHTT | |
| Ether SCHEMBL7956358 | 0.92 | TSHR (0.42) | TSHRALDH1A1LMNAKMT2AHTT | |
| SCHEMBL905407 | 0.91 | TSHR (0.47) | TSHRALDH1A1LMNAKMT2AHTT | |
| SCHEMBL19463301 | 0.91 | TSHR (0.47) | TSHRALDH1A1LMNAKMT2AHTT | |
| SCHEMBL29044559 | 0.91 | TSHR (0.47) | TSHRALDH1A1LMNAKMT2AHTT | |
| SCHEMBL19696384 | 0.90 | TSHR (0.41) | TSHRALDH1A1LMNAKMT2AHTT | |
| SCHEMBL43576 | 0.90 | PSMB8 (0.35) | TSHRLMNAKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL31522720 | 0.88 | PSMB8 (0.34) | LMNAKMT2AHTTHPGDSMN1; SMN2 | |
| SCHEMBL13183261 | 0.86 | BRD4 (0.39) | TSHRALDH1A1KMT2AHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116916965-A | Bioactive material conjugates with conjugated biotin moieties, fatty acid moieties, or combinations thereof | D&D制药技术股份有限公司 | 2023-10-20 | — | — | CN | claimed |
| EP-0396709-A4 | HUMAN LEUKOCYTE ELASTASE INHIBITORS AND METHODS OF PRODUCING AND USING SAME | — | 1991-05-22 | — | — | EP | claimed |
| EP-0396709-A1 | HUMAN LEUKOCYTE ELASTASE INHIBITORS AND METHODS OF PRODUCING AND USING SAME | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-11-14 | — | — | EP | claimed |
| EP-0367514-A2 | Human leukocyte elastase inhibitors and methods for producing and using same | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-05-09 | — | — | EP | claimed |
| WO-1990004409-A1 | HUMAN LEUKOCYTE ELASTASE INHIBITORS AND METHODS OF PRODUCING AND USING SAME | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-05-03 | — | — | WO | claimed |
| EP-3581195-B1 | ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2025-10-01 | — | — | EP | disclosed |
| EP-3492473-B1 | HAPTENS OF OLANZAPINE | JANSSEN PHARMACEUTICA NV (BE) | 2025-07-30 | — | — | EP | disclosed |
| WO-2024220546-A2 | ANTIBODIES AND ANTIBODY-DRUG CONJUGATES AND METHODS OF USE AND SYNTHETIC PROCESSES AND INTERMEDIATES | PEAK BIO, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| CN-116940384-A | Oral formulations having bioactive material conjugates coupled to biotin moieties, fatty acid moieties, or combinations thereof | D&D制药技术股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116916965-A | Bioactive material conjugates with conjugated biotin moieties, fatty acid moieties, or combinations thereof | D&D制药技术股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| US-20230321267-A1 | Method And Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
| US-11759526-B2 | Method and molecules | MEDIMMUNE, LLC (US) | 2023-09-19 | — | — | US | disclosed |
| US-20020032306-A1 | CYCLOPEPTIDE DERIVATIVES | BIOMET DEUTSCHLAND GMBH (DE) | 2002-03-14 | — | — | US | disclosed |
| US-6316669-B1 | OPHTHALMOLOGY | ALCON MANUFACTURING, LTD. | 2001-11-13 | — | — | US | disclosed |
| US-5922319-A | REDUCING SCARING IN EYES | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1999-07-13 | — | — | US | disclosed |
| EP-0396709-A4 | HUMAN LEUKOCYTE ELASTASE INHIBITORS AND METHODS OF PRODUCING AND USING SAME | — | 1991-05-22 | — | — | EP | disclosed |
| US-5008245-A | Antiinflammatory agents | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0396709-A1 | HUMAN LEUKOCYTE ELASTASE INHIBITORS AND METHODS OF PRODUCING AND USING SAME | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-11-14 | — | — | EP | disclosed |
| EP-0367514-A2 | Human leukocyte elastase inhibitors and methods for producing and using same | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-05-09 | — | — | EP | disclosed |
| WO-1990004409-A1 | HUMAN LEUKOCYTE ELASTASE INHIBITORS AND METHODS OF PRODUCING AND USING SAME | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321267-A1 | Method And Molecules | PAICS, EPCAM, SQLE | TSHR 1084/4885ALDH1A1 27/4885LMNA 1762/4885 |
| US-11759526-B2 | Method and molecules | PAICS, EPCAM, SQLE | TSHR 1084/4885ALDH1A1 27/4885LMNA 1762/4885 |
| US-20020032306-A1 | CYCLOPEPTIDE DERIVATIVES | CORO1C, CYCS, CORO1A | TSHR 1623/4885ALDH1A1 4557/4885LMNA 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.