Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13183289 | 1.00 | HMGCR (0.43) | HMGCRPTPN1TBXAS1PPARGPPARA | |
| SCHEMBL13183330 | 0.98 | HMGCR (0.41) | HMGCRPTPN1TBXAS1PPARGPPARA | |
| SCHEMBL13183245 | 0.92 | PTPN1 (0.38) | HMGCRPTPN1TBXAS1PPARGPPARA | |
| SCHEMBL4234744 | 0.86 | HMGCR (0.42) | HMGCRPTPN1TBXAS1 | |
| SCHEMBL9983184 | 0.84 | PTPN1 (0.57) | HMGCRPTPN1PPARGPPARAGMNN | |
| SCHEMBL29460064 | 0.84 | PTPN1 (0.57) | HMGCRPTPN1PPARGPPARAGMNN | |
| SCHEMBL3938657 | 0.84 | PTPN1 (0.57) | HMGCRPTPN1PPARGPPARAGMNN | |
| SCHEMBL3938661 | 0.84 | PTPN1 (0.57) | HMGCRPTPN1PPARGPPARAGMNN | |
| SCHEMBL9983182 | 0.84 | PTPN1 (0.57) | HMGCRPTPN1PPARGPPARAGMNN | |
| SCHEMBL8069384 | 0.80 | HMGCR (0.60) | HMGCRPTPN1PPARGPPARAGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240754-A1 | UNSATURATED FATTY AMINO ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY | Pierre Fabre Demo-Cosmetique (FR) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240754-A1 | UNSATURATED FATTY AMINO ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY | FFAR3, FFAR2, BCAT1 | HMGCR 1517/4885PTPN1 4204/4885TBXAS1 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.