Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 3/20 | 0.44 |
| ▸ | ACACB | O00763 | 8/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13183398 | 0.90 | ACE (0.48) | CASP1MMEACACB | |
| SCHEMBL14370014 | 0.81 | CASP1 (0.60) | CASP1GRIA1 | |
| SCHEMBL2314756 | 0.80 | CASP1 (0.61) | CASP1MMEGRIA1 | |
| SCHEMBL2314769 | 0.80 | CASP1 (0.61) | CASP1MMEGRIA1 | |
| SCHEMBL646595 | 0.79 | CASP1 (0.55) | CASP1MMEGRIA1 | |
| SCHEMBL24310822 | 0.79 | CASP1 (0.63) | CASP1GRIA1 | |
| SCHEMBL7752844 | 0.79 | CASP1 (0.55) | CASP1MMEGRIA1 | |
| SCHEMBL7702992 | 0.79 | CASP1 (0.53) | CASP1GRIA1 | |
| SCHEMBL30465924 | 0.79 | NAALAD2 (0.56) | CASP1MME | |
| SCHEMBL5689768 | 0.78 | CASP1 (0.59) | CASP1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799753-B2 | Bisubstrate inhibitors of protein tyrosine kinases as therapeutic agents | Board of Governers for Higher Education (US) | 2010-09-21 | — | — | US | disclosed |