Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | CPA1 | P15085 | 2/20 | 0.49 |
| ▸ | CPA2 | P48052 | 1/20 | 0.49 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314769 | 0.89 | CASP1 (0.61) | CASP1CPA1CPA2CPA4GRIA1 | |
| SCHEMBL2314756 | 0.89 | CASP1 (0.61) | CASP1CPA1CPA2CPA4GRIA1 | |
| SCHEMBL646595 | 0.89 | CASP1 (0.55) | CASP1CPA1CPA2CPA4GRIA1 | |
| SCHEMBL7587214 | 0.85 | SLC7A5 (0.52) | OPRD1 | |
| SCHEMBL14370014 | 0.85 | CASP1 (0.60) | CASP1CPA1CPA2CPA4GRIA1 | |
| SCHEMBL11569755 | 0.85 | FOLH1 (0.58) | CASP1CPA1BACE1BACE2FOLH1 | |
| SCHEMBL11569779 | 0.85 | FOLH1 (0.58) | CASP1CPA1BACE1BACE2FOLH1 | |
| SCHEMBL24310822 | 0.83 | CASP1 (0.63) | CASP1CPA1CPA2CPA4GRIA1 | |
| SCHEMBL30031739 | 0.83 | CASP1 (0.55) | CASP1CPA1CPA2CPA4GRIA1 | |
| SCHEMBL7702992 | 0.83 | CASP1 (0.53) | CASP1CPA1CPA2CPA4GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049856-A2 | DROSOPHILA ENZYMES, ENCODING NUCLEIC ACIDS AND METHODS OF USE | GENOPTERA, LLC (US) | 2001-07-12 | — | — | WO | disclosed |