SCHEMBL13183447

SCHEMBL13183447

O=Cc1c[nH]cc(O)c1=O

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.38
TRIM33 Q9UPN9 2/20 0.38
ERN1 O75460 10/20 0.35
PIM1 P11309 1/20 0.34
TYR P14679 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2874824 0.74
SCHEMBL10209027 0.73 GRIA1 (0.39) TRIM24TRIM33ERN1
SCHEMBL182503 0.64
SCHEMBL1703795 0.64
SCHEMBL12137341 0.64
SCHEMBL18860850 0.63 CYP2A6 (0.37) ERN1PIM1
SCHEMBL20003671 0.63 PTGS1 (0.37) PIM1
SCHEMBL16921537 0.62 GABRA1 (0.37) TYR
SCHEMBL28992032 0.61 TRIM24 (0.50) TRIM24TRIM33ERN1PIM1TYR
SCHEMBL30386098 0.61 TRIM24 (0.50) TRIM24TRIM33ERN1PIM1TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010110231-A1 SUBSTITUTED 3-HYDROXY-4-PYRIDONE DERIVATIVE 塩野義製薬株式会社 (JP) 2010-09-30 WO disclosed