Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 11/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.51 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21623941 | 0.84 | NOTUM (0.40) | ESRRANOTUMFLT3 | |
| SCHEMBL13160180 | 0.81 | NOTUM (0.51) | ESRRANOTUMAMY1AKCNH2 | |
| SCHEMBL14611001 | 0.81 | NOTUM (0.56) | NOTUMKCNH2FLT3 | |
| SCHEMBL3753945 | 0.81 | ESRRA (0.47) | ESRRANOTUMFLT3 | |
| SCHEMBL13183572 | 0.80 | NOTUM (0.59) | NOTUMFLT3 | |
| SCHEMBL25043773 | 0.80 | NOTUM (0.38) | ESRRANOTUMFLT3 | |
| SCHEMBL25494290 | 0.77 | ESRRA (0.48) | ESRRANOTUMAMY1AFLT3 | |
| SCHEMBL12179482 | 0.77 | MIF (0.53) | ESRRANOTUM | |
| SCHEMBL2683483 | 0.77 | FLT3 (0.50) | NOTUMFLT3 | |
| SCHEMBL2629357 | 0.76 | P2RX7 (0.55) | ESRRANOTUMFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100226882-A1 | LINKED DIIMIDAZOLE ANTIVIRALS | ENANTA PHARMACEUTICALS, INC. | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100226882-A1 | LINKED DIIMIDAZOLE ANTIVIRALS | EIF2AK2, ZC3HAV1, MAVS | ESRRA 3494/4885NOTUM 961/4885AMY1A 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.