Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13160096 | 0.85 | SMN1; SMN2 (0.38) | CYP11B1CYP11B2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13183799 | 0.81 | KMT2A (0.46) | CYP11B1CYP11B2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL17322383 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AL3MBTL1ATMGRM5 | |
| SCHEMBL20020222 | 0.75 | CYP11B1 (0.40) | CYP11B1CYP11B2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15932193 | 0.75 | ALDH1A1 (0.45) | CYP11B1CYP11B2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13183570 | 0.72 | CYP11B1 (0.43) | CYP11B1CYP11B2RAB9ANPC1KMT2A | |
| SCHEMBL7374833 | 0.71 | TAAR1 (0.42) | CYP11B1CYP11B2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30447931 | 0.71 | FYN (0.41) | TAAR1IDO1DAOALDH1A1CYP2D6 | |
| SCHEMBL15932194 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AL3MBTL1MAPK1TDP1 | |
| SCHEMBL4505633 | 0.70 | MAPT (0.46) | CYP11B1CYP11B2RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100226882-A1 | LINKED DIIMIDAZOLE ANTIVIRALS | ENANTA PHARMACEUTICALS, INC. | 2010-09-09 | — | — | US | disclosed |
| WO-2010096462-A1 | LINKED DIIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC (US) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100226882-A1 | LINKED DIIMIDAZOLE ANTIVIRALS | EIF2AK2, ZC3HAV1, MAVS | CYP11B1 317/4885CYP11B2 499/4885SMN1; SMN2 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.