SCHEMBL131840

SCHEMBL131840

[CH2]CCCCN(CCC)CCC

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.32
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
DRD3 P35462 1/20 0.31
KDM5A P29375 1/20 0.31
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8412354 0.97 DNM1 (0.36) DNM1KDM5A
SCHEMBL128205 0.97 DNM1 (0.36) DNM1KDM5A
SCHEMBL8409800 0.97 DNM1 (0.36) DNM1KDM5A
SCHEMBL128172 0.92 HRH3 (0.31) DRD2DRD3HRH3
SCHEMBL28199223 0.89 HRH3 (0.30) HRH3
SCHEMBL128657 0.89 KDM5A (0.38) DNM1KDM5A
SCHEMBL2045798 0.89 DNM1 (0.43) DNM1DRD2DRD3KDM5A
SCHEMBL9579283 0.87 KCNH2 (0.40) DNM1DRD3
SCHEMBL1405659 0.86 DNM1 (0.48) DNM1DRD2DRD3KDM5A
SCHEMBL5384597 0.86 DNM1 (0.42) DNM1KDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023276967-A1 OSMOREGULATOR 国立大学法人九州大学 2023-01-05 WO disclosed
US-8450319-B2 Pyrrolopyridazinone compound UBE INDUSTRIES, LTD. (JP) 2013-05-28 US disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
EP-1982986-B1 PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR UBE INDUSTRIES (JP) 2012-03-07 EP disclosed
US-7563580-B2 Nucleic acid adsorbent; methods for adsorbing, removing, dissociating, and recovering nucleic acids using the same; and method for regenerating the same CHISSO CORPORATION (JP) 2009-07-21 US disclosed
US-20090036453-A1 Pyrrolopyridazinone Compound UBE INDUSTRIES, LTD. (JP) 2009-02-05 US disclosed
EP-1982986-A1 PYRROLOPYRIDAZINONE COMPOUND Ube Industries, Ltd. (JP) 2008-10-22 EP disclosed
US-20080227969-A1 Nucleic acid adsorbent; methods for adsorbing, removing, dissociating, and recovering nucleic acids using the same; and method for regenerating the same JNC CORPORATION (JP) 2008-09-18 US disclosed
US-7358050-B2 Nucleic acid adsorbent; methods for adsorbing, removing, dissociating, and recovering nucleic acids using the same; and method for regenerating the same CHISSO CORPORATION (JP) 2008-04-15 US disclosed
US-5443829-A For enhancing delivery of drugs across mucous membranes of animals CAMBRIDGE BIOTECH CORPORATION (US) 1995-08-22 US disclosed
EP-0658111-A1 METHODS FOR ENHANCING DRUG DELIVERY WITH MODIFIED SAPONINS CAMBRIDGE BIOTECH CORPORATION (US) 1995-06-21 EP disclosed
EP-0645368-A1 Process for the purification of tertiary amines from primary and secondary amines BASF Aktiengesellschaft (DE) 1995-03-29 EP disclosed
WO-1994001118-A1 METHODS FOR ENHANCING DRUG DELIVERY WITH MODIFIED SAPONINS CAMBRIDGE BIOTECH CORPORATION (US) 1994-01-20 WO disclosed
US-5273965-A A reduced and hydrolyzed saponin from a Quillaja saponaria extract CAMBRIDGE BIOTECH CORPORATION (US) 1993-12-28 US disclosed
US-4351768-A CARBONLESS, DUPLICATION, INDOLE DYES STERLING DRUG INC. (US) 1982-09-28 US disclosed
US-4322352-A Indolyl phthalide compounds STERLING DRUG INC. (US) 1982-03-30 US disclosed
US-4307018-A CHROMOGENS FOR COPYING SYSTEMS STERLING DRUG INC. (US) 1981-12-22 US disclosed
US-4251446-A COLOR PRECURSORS STERLING DRUG INC. (US) 1981-02-17 US disclosed
US-4189171-A PRESSURE SENSITIVE, THERMAL AND HECTOGRAPHIC SYSTEMS STERLING DRUG INC. (US) 1980-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227969-A1 Nucleic acid adsorbent; methods for adsorbing, removing, dissociating, and recovering nucleic acids using the same; and method for regenerating the same DNMT1, NSUN2, DNA2 DNM1 2166/4885DRD2 4047/4885DRD4 3891/4885
US-20090036453-A1 Pyrrolopyridazinone Compound CBR3, CBR1, CYC1 DNM1 3297/4885DRD2 169/4885DRD4 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.