SCHEMBL128172

SCHEMBL128172

[CH2]CCCN(CCC)CCC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.31
HTR1A P08908 1/20 0.30
DRD2 P14416 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28199223 0.97 HRH3 (0.30) HRH3
SCHEMBL5262504 0.95 CA12 (0.34)
SCHEMBL131840 0.92 DNM1 (0.32) HRH3DRD2DRD3
SCHEMBL8409800 0.89 DNM1 (0.36)
SCHEMBL128205 0.89 DNM1 (0.36)
SCHEMBL8412354 0.89 DNM1 (0.36)
SCHEMBL737146 0.89 KCNH2 (0.35) HTR1ADRD3
SCHEMBL129571 0.88 CA12 (0.37)
SCHEMBL21065760 0.86 CA12 (0.36) DRD2DRD3
SCHEMBL3480698 0.86 DNM1 (0.43) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10294260-B2 Tetracyclic anthraquinone derivatives TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) 2019-05-21 US claimed
EP-3428202-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM ExxonMobil Chemical Patents Inc. (US) 2019-01-16 EP claimed
US-20170247403-A1 TETRACYCLIC ANTHRAQUINONE DERIVATIVES TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) 2017-08-31 US claimed
US-9725589-B2 Method of preparing acrylic polymers and products produced thereby LUBRIZOL ADVANCED MATERIALS, INC. (US) 2017-08-08 US claimed
US-9670242-B2 Tetracyclic anthraquinone derivatives TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) 2017-06-06 US claimed
EP-2824108-B1 TETRACYCLIC ANTHRAQUINONE DERIVATIVES TIANJIN HEMAY BIO-TECH CO LTD (CN) 2017-04-19 EP claimed
CN-104125962-B tetracyclic anthraquinone derivatives 天津和美生物技术有限公司 2016-06-22 CN claimed
EP-2984111-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM ExxonMobil Chemical Patents Inc. (US) 2016-02-17 EP claimed
US-20150166595-A1 Tetracyclic Anthraquinone Derivatives TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) 2015-06-18 US claimed
EP-2824108-A1 TETRACYCLIC ANTHRAQUINONE DERIVATIVES Tianjin Hemay Bio-Tech Co., Ltd. (CN) 2015-01-14 EP claimed
EP-1988873-B1 POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME LUBRIZOL ADVANCED MAT INC (US) 2013-01-09 EP claimed
EP-2039343-B1 Cosmetic compositions containing a cationic copolymer and a particular amino silicone and uses thereof OREAL (FR) 2012-12-05 EP claimed
EP-1647555-B1 THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME INST RADIATION MED AMMS PLA (CN) 2011-04-20 EP claimed
US-7727965-B2 C-glycosylisoflavones having alkylaminoalkoxyl substituent, preparation and use of the same HAINAN YANGPU NEW & SPECIAL MEDICINE CO., LTD. (CN) 2010-06-01 US claimed
US-20090074696-A1 COSMETIC COMPOSITION COMPRISING A CATIONIC COPOLYMER AND A STARCH AND COSMETIC TREATMENT PROCESS THEREOF L'OREAL S.A. (FR) 2009-03-19 US claimed
US-20080293642-A1 C-Glycosylisoflavones Having Alkylaminoalkoxyl Substituent, Preparation and Use of the Same INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) 2008-11-27 US claimed
EP-1647555-A1 THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME Institute of Radiation Medicine Academy of Military Medical Sciences of the Pla (CN) 2006-04-19 EP claimed
EP-0670838-A1 SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1995-09-13 EP claimed
US-5321057-A Ammonium polyphosphate microencapsulated with aminoplastic resins MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1994-06-14 US claimed
US-3933800-A O-SUBSTITUTED OXIMES, MICROBIOCIDES GRUPPO LEPETIT S.P.A. (IT) 1976-01-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293642-A1 C-Glycosylisoflavones Having Alkylaminoalkoxyl Substituent, Preparation and Use of the Same UGCG, PIGO, GPI HRH3 3150/4885HTR1A 3438/4885DRD2 3589/4885
US-20150166595-A1 Tetracyclic Anthraquinone Derivatives ANTXR2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TBXA2R HRH3 370/4885HTR1A 3443/4885DRD2 3001/4885
US-10294260-B2 Tetracyclic anthraquinone derivatives H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, F12, ANTXR2 HRH3 655/4885HTR1A 4449/4885DRD2 3114/4885
US-20090074696-A1 COSMETIC COMPOSITION COMPRISING A CATIONIC COPOLYMER AND A STARCH AND COSMETIC TREATMENT PROCESS THEREOF TYR, OXGR1, OGFOD1 HRH3 229/4885HTR1A 754/4885DRD2 1592/4885
US-20170247403-A1 TETRACYCLIC ANTHRAQUINONE DERIVATIVES ANTXR2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TBXA2R HRH3 370/4885HTR1A 3443/4885DRD2 3001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.