Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.33 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.33 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317537 | 0.93 | TDP1 (0.36) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL1316980 | 0.93 | TDP1 (0.36) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL1319978 | 0.91 | TDP1 (0.35) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL26780258 | 0.90 | TDP1 (0.41) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL706579 | 0.90 | TDP1 (0.41) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL25608882 | 0.87 | TDP1 (0.35) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL29707946 | 0.87 | TDP1 (0.35) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL16243030 | 0.86 | SLC28A1 (0.33) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL12212785 | 0.86 | TDP1 (0.36) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL15261259 | 0.86 | TDP1 (0.33) | TDP1P2RY2SLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536318-B2 | Chemical RNA synthesis method | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-09-17 | — | — | US | disclosed |
| EP-2303905-B1 | CHEMICAL RNA SYNTHESIS METHOD | CENTRE NAT RECH SCIENT (FR) | 2012-11-28 | — | — | EP | disclosed |
| US-20110275793-A1 | Chemical RNA Synthesis Method | CHEMGENES CORPORATION | 2011-11-10 | — | — | US | disclosed |
| EP-2303905-A1 | CHEMICAL RNA SYNTHESIS METHOD | Centre National de la Recherche Scientifique (FR) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009144418-A1 | CHEMICAL RNA SYNTHESIS METHOD | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275793-A1 | Chemical RNA Synthesis Method | NSUN3, POLR2E, POLR2H | TDP1 2936/4885P2RY2 3875/4885SLC28A1 3400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.