SCHEMBL1318521

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1318732	0.91	PDPK1 (0.51)	PDPK1AURKAROCK1AURKBMTOR
	SCHEMBL1319013	0.90	PDPK1 (0.57)	PDPK1AURKAROCK1AURKBMTOR
	SCHEMBL1317622	0.89	AURKA (0.37)	PDPK1AURKAROCK1AURKBMTOR
	SCHEMBL1318623	0.80	PDPK1 (0.61)	PDPK1AURKAROCK1AURKBMTOR
	SCHEMBL1318542	0.79	PDPK1 (0.68)	PDPK1AURKAROCK1AURKBLRRK2
	SCHEMBL1317566	0.79	AURKA (0.39)	PDPK1AURKAROCK1AURKBMTOR
	SCHEMBL1317828	0.79	PDPK1 (0.57)	PDPK1AURKAROCK1AURKBMTOR
	SCHEMBL1319287	0.77	PDPK1 (0.55)	PDPK1AURKAROCK1AURKBMTOR
	SCHEMBL1318487	0.77	AURKA (0.42)	PDPK1AURKAROCK1AURKBMTOR
	SCHEMBL2512987	0.77	AURKA (0.42)	PDPK1AURKAROCK1AURKBMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.