Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12429139 | 1.00 | MEN1 (0.32) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL16070751 | 0.80 | PNMT (0.31) | — | |
| SCHEMBL9494233 | 0.80 | CHAT (0.40) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL9494239 | 0.80 | CHAT (0.40) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL31094912 | 0.80 | CHAT (0.40) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL19188151 | 0.80 | CHAT (0.40) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL13782928 | 0.79 | PTGER4 (0.34) | PTGER3PTGER2PTGER4 | |
| SCHEMBL7959776 | 0.78 | PNMT (0.41) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL7959778 | 0.78 | PNMT (0.41) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL13782978 | 0.78 | PTGER4 (0.32) | PTGER3PTGER2PTGER4NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010099527-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010091413-A1 | LINKED DIBENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |