Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959776 | 1.00 | PNMT (0.41) | PNMTDPP4TAAR1LOXL2MEN1 | |
| SCHEMBL16935678 | 0.82 | PNMT (0.44) | PNMTDPP4TAAR1LOXL2NCF1 | |
| SCHEMBL21168535 | 0.81 | PTGER3 (0.45) | TAAR1MEN1KMT2APTGER3PTGER2 | |
| SCHEMBL9494233 | 0.80 | CHAT (0.40) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL31094912 | 0.80 | CHAT (0.40) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL19188151 | 0.80 | CHAT (0.40) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL9494239 | 0.80 | CHAT (0.40) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL13187948 | 0.78 | MEN1 (0.32) | MEN1KMT2APTGER3PTGER2PTGER4 | |
| SCHEMBL18193098 | 0.78 | PNMT (0.41) | PNMTDPP4TAAR1LOXL2PTGER3 | |
| SCHEMBL6725286 | 0.78 | PNMT (0.41) | PNMTDPP4TAAR1LOXL2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313139-B1 | ADMINISTERING BENZYLAMINE DERIVATIVE FOR THERAPY OF PSYCHIATRIC DISORDER IN MAMMALS | AKZO NOBEL N. V. (NL) | 2001-11-06 | — | — | US | disclosed |
| EP-1035843-A2 | I h?-MODULATORS | Akzo Nobel N.V. (NL) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999018941-A2 | Ih-MODULATORS | AKZO NOBEL N.V. (NL) | 1999-04-22 | — | — | WO | disclosed |
| CN-1036993-C | Aromatase inhibiting 4(5)-imidazoles | FARMOS OY (FI) | 1998-01-14 | — | — | CN | disclosed |
| US-4906634-A | Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents | SCHERING A.G. (DE) | 1990-03-06 | — | — | US | disclosed |
| EP-0332570-A2 | Novel-N-(4-(Aminosubstituted)phenyl) methanesulfonamides and their use as cardiovascular agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-09-13 | — | — | EP | disclosed |
| CN-1033995-A | 4 (5)-imidazoles that suppress aromatase enzyme | FARMOS OY (FI) | 1989-07-19 | — | — | CN | disclosed |