Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 13/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188946 | 0.85 | PIK3CG (0.74) | PIK3CGPIK3CAABL1 | |
| SCHEMBL13188161 | 0.83 | PIK3CG (0.51) | PIK3CGPIK3CAABL1 | |
| SCHEMBL13189027 | 0.82 | PIK3CG (0.50) | PIK3CGPIK3CADYRK1AABL1 | |
| SCHEMBL3782341 | 0.80 | PIK3CG (0.56) | PIK3CGPIK3CADYRK1AABL1 | |
| SCHEMBL13188923 | 0.80 | PIK3CG (0.49) | PIK3CGPIK3CADYRK1AABL1 | |
| SCHEMBL13188913 | 0.80 | KDM4E (0.39) | PIK3CGPIK3CADYRK1AABL1 | |
| SCHEMBL3713632 | 0.80 | PIK3CG (0.49) | PIK3CGPIK3CADYRK1AABL1 | |
| SCHEMBL12543666 | 0.78 | PIK3CG (0.48) | PIK3CGABL1 | |
| SCHEMBL13189215 | 0.77 | KMT2A (0.53) | PIK3CGPIK3CAABL1 | |
| SCHEMBL12543196 | 0.77 | PIK3CG (0.48) | PIK3CGPIK3CADYRK1AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100144-A1 | FUSED BICYCLIC COMPOUNDS AS INHIBITORS FOR PI3 KINASE | MERCK SERONO S.A. (CH) | 2010-09-10 | — | — | WO | disclosed |