Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15220107 | 0.93 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13188795 | 0.90 | NPC1 (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL989681 | 0.88 | CCR6 (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7355378 | 0.88 | HTT (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16667746 | 0.87 | SMN1; SMN2 (0.42) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7359293 | 0.85 | HTT (0.53) | NPC1RAB9ASMN1; SMN2LMNACCR6 | |
| SCHEMBL9228433 | 0.84 | HTT (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7352889 | 0.84 | HTT (0.52) | NPC1RAB9ASMN1; SMN2LMNACCR6 | |
| SCHEMBL8029842 | 0.83 | HTT (0.51) | SMN1; SMN2LMNACCR6PAX8CA12 | |
| SCHEMBL7357380 | 0.83 | HTT (0.51) | SMN1; SMN2LMNACCR6PAX8CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096854-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC3 AND/OR MC4 RECEPTORS AND TREATMENT OF CONDITIONS RELATED TO THESE RECEPTORS | MIMETICA PTY LTD (AU) | 2010-09-02 | — | — | WO | disclosed |