Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357380 | 0.99 | HTT (0.51) | HTTCCR6PAX8ALOX5FOLH1 | |
| SCHEMBL8029842 | 0.99 | HTT (0.51) | HTTCCR6PAX8ALOX5FOLH1 | |
| SCHEMBL7359293 | 0.96 | HTT (0.53) | HTTCCR6PAX8FOLH1CPB1 | |
| SCHEMBL7355378 | 0.93 | HTT (0.50) | HTTCCR6PAX8FOLH1CPB1 | |
| SCHEMBL989681 | 0.93 | CCR6 (0.48) | HTTCCR6PAX8CTSLLMNA | |
| SCHEMBL8039584 | 0.91 | CCR6 (0.43) | HTTCCR6PAX8CTSLCA12 | |
| SCHEMBL15220107 | 0.87 | ALDH1A1 (0.43) | HTTCCR6PAX8CTSLLMNA | |
| SCHEMBL16667746 | 0.84 | SMN1; SMN2 (0.42) | HTTCCR6PAX8LMNASMN1; SMN2 | |
| SCHEMBL13189129 | 0.84 | NPC1 (0.43) | HTTCCR6PAX8CTSLLMNA | |
| SCHEMBL9228433 | 0.84 | HTT (0.45) | HTTCCR6PAX8LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048911-A1 | MONOBACTAM ENZYME INHIBITORS | NAEJA PHARMACEUTICAL INC. (GB) | 1999-09-30 | — | — | WO | disclosed |
| EP-0646573-A1 | Preparation of protected and unprotected guanidino-substituted carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-05 | — | — | EP | disclosed |