Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | FABP7 | O15540 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13878698 | 0.79 | KMT2A (0.65) | KMT2ACASP3EPHX2FABP5TNF | |
| SCHEMBL18811279 | 0.79 | KMT2A (0.70) | KMT2ACASP3EPHX2FABP5 | |
| SCHEMBL20759696 | 0.77 | KMT2A (0.78) | KMT2ACASP3EPHX2TLR2 | |
| SCHEMBL6187733 | 0.76 | KMT2A (0.65) | KMT2ACASP3EPHX2FABP5FABP7 | |
| SCHEMBL2632350 | 0.75 | KMT2A (0.62) | KMT2ACASP3EPHX2CA1CA2 | |
| SCHEMBL16697162 | 0.75 | KMT2A (0.50) | KMT2ACASP3EPHX2CA1CA2 | |
| SCHEMBL6673820 | 0.74 | KMT2A (0.64) | KMT2ACASP3EPHX2CA1CA2 | |
| SCHEMBL13613350 | 0.74 | KMT2A (0.72) | KMT2ACASP3EPHX2CA1CA2 | |
| SCHEMBL29771910 | 0.73 | CASP3 (0.51) | KMT2ACASP3EPHX2 | |
| SCHEMBL12391727 | 0.73 | KMT2A (0.57) | KMT2ACASP3EPHX2FABP5FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010106441-A2 | PEPTIDOMIMETICS FOR MODULATING INTERLEUKIN-1 RECEPTOR | CENTRE HOSPITALIER UNIVERSITAIRE SAINTE-JUSTINE (CA) | 2010-09-23 | — | — | WO | disclosed |