Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 11/20 | 0.37 |
| ▸ | DRD1 | P21728 | 10/20 | 0.37 |
| ▸ | DRD4 | P21917 | 10/20 | 0.37 |
| ▸ | HTR2C | P28335 | 10/20 | 0.37 |
| ▸ | DRD2 | P14416 | 10/20 | 0.37 |
| ▸ | DRD5 | P21918 | 6/20 | 0.37 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188849 | 0.86 | OPRM1 (0.42) | OPRM1TMEM97SIGMAR1DRD3DRD2 | |
| SCHEMBL13689518 | 0.81 | OPRM1 (0.47) | OPRM1TMEM97SIGMAR1HDAC3HDAC4 | |
| SCHEMBL13188826 | 0.80 | OPRM1 (0.49) | OPRM1TMEM97SIGMAR1DRD3DRD2 | |
| SCHEMBL13190968 | 0.79 | OPRM1 (0.46) | OPRM1TMEM97SIGMAR1DRD3DRD4 | |
| SCHEMBL13190973 | 0.78 | OPRM1 (0.41) | OPRM1TMEM97SIGMAR1DRD3DRD1 | |
| SCHEMBL13188835 | 0.78 | OPRM1 (0.44) | OPRM1TMEM97SIGMAR1HDAC3HDAC4 | |
| SCHEMBL13188839 | 0.76 | TMEM97 (0.42) | OPRM1TMEM97SIGMAR1DRD3DRD1 | |
| SCHEMBL13691796 | 0.76 | OPRM1 (0.38) | OPRM1TMEM97SIGMAR1DRD3DRD4 | |
| SCHEMBL13689530 | 0.75 | OPRM1 (0.42) | OPRM1TMEM97SIGMAR1DRD3DRD2 | |
| SCHEMBL13691803 | 0.75 | ITGB3 (0.38) | OPRM1TMEM97SIGMAR1DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096853-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC1 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR | MIMETICA PTY LTD (AU) | 2010-09-02 | — | — | WO | disclosed |