Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CBLB | Q13191 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135382 | 0.85 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL15641849 | 0.83 | KDM4E (0.38) | KMT2AALDH1A1 | |
| SCHEMBL21783321 | 0.83 | CBLB (0.43) | CBLBKMT2AATM | |
| SCHEMBL15641911 | 0.82 | KDM4E (0.41) | KMT2AALDH1A1 | |
| SCHEMBL15641923 | 0.82 | KDM4E (0.41) | KMT2AALDH1A1 | |
| SCHEMBL15642204 | 0.82 | KDM4E (0.41) | KMT2AALDH1A1 | |
| SCHEMBL15641870 | 0.82 | KDM4E (0.41) | KMT2AALDH1A1 | |
| SCHEMBL23375507 | 0.81 | CBLB (0.42) | CBLBKMT2AATM | |
| SCHEMBL18327380 | 0.81 | CBLB (0.42) | CBLBKMT2AATM | |
| SCHEMBL18327379 | 0.81 | CBLB (0.42) | CBLBKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707180-B1 | WATER SOLUBLE COPOLYMERS | WACKER CHEMIE AG (DE) | 2021-05-05 | — | — | EP | disclosed |
| US-20210108013-A1 | WATER-SOLUBLE COPOLYMERS | WACKER CHEMIE AG (DE) | 2021-04-15 | — | — | US | disclosed |
| EP-2406328-B1 | AQUEOUS SILANIZED SILICA DISPERSION | NOURYON CHEMICALS INT BV (NL) | 2020-05-06 | — | — | EP | disclosed |
| US-9850327-B2 | Use of modified water-soluble polymers as crosslinking auxiliary agents | WACKER CHEMIE AG (DE) | 2017-12-26 | — | — | US | disclosed |
| EP-3049450-B1 | USE OF MODIFIED WATER-SOLUBLE POLYMERS AS CROSSLINKING AUXILIARY AGENTS | WACKER CHEMIE AG (DE) | 2017-11-08 | — | — | EP | disclosed |
| US-9453124-B2 | Modified composite particles | WACKER CHEMIE AG (DE) | 2016-09-27 | — | — | US | disclosed |
| US-20160208031-A1 | USE OF MODIFIED WATER-SOLUBLE POLYMERS AS CROSSLINKING AUXILIARY AGENTS | WACKER CHEMIE AG (DE) | 2016-07-21 | — | — | US | disclosed |
| US-9187647-B2 | Aqueous silanized silica dispersion | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2015-11-17 | — | — | US | disclosed |
| US-9090795-B2 | Method for producing composite particles | WACKER CHEMIE AG (DE) | 2015-07-28 | — | — | US | disclosed |
| US-20130337266-A1 | MODIFIED COMPOSITE PARTICLES | WACKER CHEMIE AG (DE) | 2013-12-19 | — | — | US | disclosed |
| EP-1382621-A1 | Silane containing polyvinyl alcohol for coating compositions | Wacker Polymer Systems GmbH & Co. KG (DE) | 2004-01-21 | — | — | EP | disclosed |
| EP-1080940-B1 | Water resistant composition, coating agent, and recording material | KURARAY CO (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-6346570-B1 | COMPOSITION COMPRISING UNIFORM MIXTURE OF MODIFIED POLYVINYL ALCOHOL CONTAINING ALPHA-OLEFIN UNITS WITH NOT MORE THAN 4 CARBON ATOMS AND/OR SILYL GROUPS AND ORGANOTITANIUM COMPOUND HAVING CHELATING LIGAND AT SPECIFIED BLEND RATIO | KURARAY CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1080940-A2 | Water resistant composition, coating agent, and recording material | KURARAY CO., LTD. (JP) | 2001-03-07 | — | — | EP | disclosed |
| EP-0187673-B1 | WATER RESISTANT COMPOSITION AND HEAT-SENSITIVE RECORDING SHEET CONTAINING THE SAME | KURARAY CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| EP-0123927-B1 | WATER RESISTANT COMPOSITIONS | KURARAY CO., LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |
| US-4708947-A | POLYVINYL ALCOHOL, A CHITOSAN AND AN ALDEHYDE | KURARAY CO., LTD. (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0187673-A2 | Water resistant composition and heat-sensitive recording sheet containing the same | KURARAY CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |
| US-4567221-A | DEFOGGING AGENTS, SOLIDIFICATION OF SOILS | KURARAY CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
| EP-0123927-A2 | Water resistant compositions | KURARAY CO., LTD. (JP) | 1984-11-07 | — | — | EP | disclosed |