Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | CASP1 | P29466 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19609002 | 0.85 | KMT2A (0.53) | ALDH1A1HSD17B10TSHRMAPTSMN1; SMN2 | |
| SCHEMBL27961756 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRMAPTSMN1; SMN2 | |
| SCHEMBL28129642 | 0.79 | ESR1 (0.56) | ALDH1A1HSD17B10TSHRMAPTSMN1; SMN2 | |
| SCHEMBL13382365 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HSD17B10TSHRMAPTSMN1; SMN2 | |
| SCHEMBL1263246 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TSHRMAPTMAPK1 | |
| SCHEMBL30123188 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TSHRMAPTMAPK1 | |
| SCHEMBL12202345 | 0.77 | ESR1 (0.46) | ALDH1A1HSD17B10TSHRMAPTSMN1; SMN2 | |
| SCHEMBL1502392 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HSD17B10TSHRMAPTSMN1; SMN2 | |
| SCHEMBL1187919 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRMAPTSMN1; SMN2 | |
| SCHEMBL19608972 | 0.75 | ADORA2A (0.56) | ALDH1A1HSD17B10TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9085511-B2 | Atropisomeric 1,8-bisphenolnapthalenes and their use in enantioselective recognition and asymmetric synthesis | GEORGETOWN UNIVERSITY (US) | 2015-07-21 | — | — | US | disclosed |
| US-9085511-B2 | Atropisomeric 1,8-bisphenolnapthalenes and their use in enantioselective recognition and asymmetric synthesis | GEORGETOWN UNIVERSITY (US) | 2015-07-21 | — | — | US | disclosed |
| US-20140128637-A1 | ATROPISOMERIC 1,8-BISPHENOLNAPTHALENES AND THEIR USE IN ENANTIOSELECTIVE RECOGNITION AND ASYMMETRIC SYNTHESIS | NATIONAL SCIENCE FOUNDATION | 2014-05-08 | — | — | US | disclosed |
| US-20140128637-A1 | ATROPISOMERIC 1,8-BISPHENOLNAPTHALENES AND THEIR USE IN ENANTIOSELECTIVE RECOGNITION AND ASYMMETRIC SYNTHESIS | NATIONAL SCIENCE FOUNDATION | 2014-05-08 | — | — | US | disclosed |
| WO-2012138654-A2 | ATROPISOMERIC 1,8-BISPHENOLNAPTHALENES AND THEIR USE IN ENANTIOSELECTIVE RECOGNITION AND ASYMMETRIC SYNTHESIS | GEORGETOWN UNIVERSITY (US) | 2012-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140128637-A1 | ATROPISOMERIC 1,8-BISPHENOLNAPTHALENES AND THEIR USE IN ENANTIOSELECTIVE RECOGNITION AND ASYMMETRIC SYNTHESIS | CYP2A7, CYP4A11, CYP2C8 | ALDH1A1 587/4885HSD17B10 152/4885TSHR 3248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.