SCHEMBL28129642

SCHEMBL28129642

c1ccc2cc3c(-c4c5ccccc5nc5ccccc45)cccc3cc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.56
ESR2 Q92731 6/20 0.56
ALDH1A1 P00352 6/20 0.46
MAPT P10636 3/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
GPR55 Q9Y2T6 1/20 0.46
GLA P06280 4/20 0.46
HPGD P15428 4/20 0.46
KMT2A Q03164 3/20 0.46
KDM4E B2RXH2 3/20 0.46
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27961756 0.87 ALDH1A1 (0.56) ESR1ESR2ALDH1A1MAPTLMNA
SCHEMBL28576924 0.86 CES1 (0.53) ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C19
SCHEMBL5713430 0.86 CES1 (0.48) ESR1ESR2ALDH1A1MAPTSMN1; SMN2
SCHEMBL19609002 0.84 KMT2A (0.53) ESR1ESR2ALDH1A1MAPTLMNA
SCHEMBL8361231 0.81 ALDH1A1 (0.52) ALDH1A1MAPTCYP1A2CYP3A4HPGD
SCHEMBL13192514 0.79 ALDH1A1 (0.50) ESR1ESR2ALDH1A1MAPTLMNA
SCHEMBL6242477 0.78 ALDH1A1 (0.48) ALDH1A1MAPTCYP1A2CYP3A4HPGD
Hydrazine SCHEMBL2329114 0.78 ALDH1A1 (0.48) ALDH1A1MAPTSMN1; SMN2CYP1A2CYP3A4
SCHEMBL13382365 0.78 ALDH1A1 (0.57) ESR1ESR2ALDH1A1MAPTLMNA
SCHEMBL29354014 0.77 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107337643-A A kind of acridine compound and its organic luminescent device 长春海谱润斯科技有限公司 2017-11-10 CN disclosed
CN-106486607-A Light-emitting component, light-emitting device, electronic equipment and illuminator 株式会社半导体能源研究所 2017-03-08 CN disclosed
CN-106432157-A ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE 株式会社半导体能源研究所 2017-02-22 CN disclosed