SCHEMBL13192519

SCHEMBL13192519

FC(F)(F)CCNc1cc(Br)cn2c(I)cnc12

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TTK P33981 2/20 0.33
IRAK4 Q9NWZ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13193206 0.80 TRIM33 (0.38)
SCHEMBL456244 0.77 TTK (0.33) TTKIRAK4
SCHEMBL12986953 0.74 L3MBTL1 (0.47) TTK
SCHEMBL13193098 0.73 TTK (0.45) TTK
SCHEMBL13193087 0.73 TTK (0.45) TTK
SCHEMBL456366 0.72 ERN1 (0.34) TTKIRAK4
SCHEMBL12986902 0.71 TTK (0.57) TTK
SCHEMBL13193008 0.71 TTK (0.56) TTK
SCHEMBL455984 0.70
SCHEMBL12986378 0.70 TTK (0.59) TTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012136531-A1 SUBSTITUTED IMIDAZOPYRIDINES AND INTERMEDIATES THEREOF BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-10-11 WO disclosed