Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | LPO | P22079 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937540 | 0.89 | KMT2A (0.38) | MEN1KMT2AFDPSNAMPTLPO | |
| SCHEMBL48932 | 0.82 | — | — | |
| SCHEMBL1833677 | 0.81 | FDPS (0.41) | MEN1KMT2AFDPSNAMPTLPO | |
| SCHEMBL13661117 | 0.81 | OPRK1 (0.42) | MEN1KMT2AFDPSLPOOPRK1 | |
| Hydrochloric Acid SCHEMBL30754387 | 0.80 | FDPS (0.43) | MEN1KMT2AFDPSLPOOPRK1 | |
| SCHEMBL30101478 | 0.80 | FDPS (0.43) | MEN1KMT2AFDPSLPOOPRK1 | |
| Ammonia Solution, Strong SCHEMBL27683928 | 0.80 | FDPS (0.43) | MEN1KMT2AFDPSLPOOPRK1 | |
| Iodide SCHEMBL633577 | 0.80 | FDPS (0.43) | MEN1KMT2AFDPSLPOOPRK1 | |
| Bromide SCHEMBL27242084 | 0.80 | FDPS (0.43) | MEN1KMT2AFDPSLPOOPRK1 | |
| Hydrochloric Acid SCHEMBL26676426 | 0.80 | FDPS (0.43) | MEN1KMT2AFDPSLPOOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107605-A1 | CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2010-09-23 | — | — | WO | disclosed |