Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5817644 | 0.92 | EPHX2 (0.65) | EPHX2CNR1SLC6A5 | |
| SCHEMBL29255848 | 0.83 | CASP2 (0.64) | EPHX2FAAH | |
| SCHEMBL7343085 | 0.83 | CASP2 (0.64) | EPHX2FAAH | |
| SCHEMBL13192975 | 0.82 | EPHX2 (0.71) | EPHX2FAAHTRPV1 | |
| SCHEMBL15633428 | 0.81 | EPHX2 (0.73) | EPHX2CNR1SLC6A5TRPV1 | |
| SCHEMBL18560547 | 0.80 | EPHX2 (0.62) | EPHX2CNR1SLC6A5FAAHTRPV1 | |
| SCHEMBL18683587 | 0.80 | EPHX2 (0.62) | EPHX2CNR1SLC6A5FAAH | |
| SCHEMBL21674058 | 0.80 | EPHX2 (0.62) | EPHX2CNR1SLC6A5FAAHTRPV1 | |
| SCHEMBL22996119 | 0.79 | EPHX2 (0.69) | EPHX2CNR1SLC6A5FAAHTRPV1 | |
| SCHEMBL10888874 | 0.79 | EPHX2 (0.69) | EPHX2CNR1SLC6A5FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012138706-A1 | EPOXYEICOSATRIENOIC ACID ANALOGS AND METHODS OF MAKING AND USING THE SAME | MCW RESEARCH FOUNDATION, INC. (US) | 2012-10-11 | — | — | WO | disclosed |