Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.64 |
| ▸ | NAAA | Q02083 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.59 |
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29255848 | 1.00 | CASP2 (0.64) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL5817644 | 0.91 | EPHX2 (0.65) | EPHX2 | |
| SCHEMBL25122098 | 0.90 | CASP2 (0.62) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL25091538 | 0.90 | CASP2 (0.62) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL27509598 | 0.88 | SLC6A5 (0.56) | CASP2NAAAEPHX1 | |
| SCHEMBL27771211 | 0.88 | SLC6A5 (0.56) | CASP2NAAAEPHX1 | |
| SCHEMBL25716051 | 0.88 | CASP2 (0.59) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL23589944 | 0.86 | CASP2 (0.58) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL3419664 | 0.86 | FAAH (0.53) | CASP2NAAAEPHX1FAAHMEN1 | |
| SCHEMBL28770694 | 0.85 | EPHX1 (0.49) | CASP2NAAAEPHX1FAAHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639468-A | Derivatives of glycinamide, their preparation and their use | CONTINENTAL PHARMA INC. (BE) | 1987-01-27 | — | — | US | disclosed |