SCHEMBL13192827

SCHEMBL13192827

O=C(N1CCCCC1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DAGLA Q9Y4D2 13/20 1.00
▸ ABHD6 Q9BV23 4/20 1.00
▸ DAGLB Q8NCG7 10/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18936598 0.94 DAGLA (0.92) DAGLAABHD6DAGLB
SCHEMBL20575830 0.94 DAGLA (1.00) DAGLAABHD6DAGLB
SCHEMBL15426552 0.93 DAGLA (0.86) DAGLAABHD6DAGLB
SCHEMBL13192823 0.93 DAGLA (0.86) DAGLAABHD6DAGLB
SCHEMBL18935806 0.92 DAGLB (1.00) DAGLAABHD6DAGLB
SCHEMBL15426548 0.92 DAGLA (0.84) DAGLAABHD6DAGLB
SCHEMBL15427259 0.92 DAGLA (0.84) DAGLAABHD6DAGLB
SCHEMBL30095999 0.92 DAGLA (0.84) DAGLAABHD6DAGLB
SCHEMBL20575921 0.91 DAGLA (1.00) DAGLAABHD6DAGLB
SCHEMBL20576067 0.91 DAGLA (1.00) DAGLAABHD6DAGLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119709988-A Multiplex fluorescence ARMS-PCR detection method for genotyping beef cattle genetic defect marker loci 全国畜牧总站 2025-03-28 — — CN disclosed
CN-119464463-A Genetic sex-specific multiplex molecular marker for palace goldfish, kit and application thereof 北京市水产技术推广站(北京市鱼病防治站) 2025-02-18 — — CN disclosed
WO-2025017210-A1 MONOGLYCERIDE LIPASE INHIBITORS IN THE TREATMENT OF PANCREATIC CANCER KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-01-23 — — WO disclosed
WO-2022179561-A1 NEUTRALIZING ANTIBODIES AGAINST COVID-19 AND METHODS OF USE THEREOF THE UNIVERSITY OF HONG KONG (CN) 2022-09-01 — — WO disclosed
US-9108930-B2 N1- and N2-carbamoyl-1,2,3-triazole serine hydrolase inhibitors and methods THE SCRIPPS RESEARCH INSTITUTE (US) 2015-08-18 — — US disclosed
US-9108930-B2 N1- and N2-carbamoyl-1,2,3-triazole serine hydrolase inhibitors and methods THE SCRIPPS RESEARCH INSTITUTE (US) 2015-08-18 — — US disclosed
US-20140018318-A1 N1- and N2-CARBAMOYL-1,2,3-TRIAZOLE SERINE HYDROLASE INHIBITORS AND METHODS THE SCIPPS RESEARCH INSTITUTE (US) 2014-01-16 — — US disclosed
US-20140018318-A1 N1- and N2-CARBAMOYL-1,2,3-TRIAZOLE SERINE HYDROLASE INHIBITORS AND METHODS THE SCIPPS RESEARCH INSTITUTE (US) 2014-01-16 — — US disclosed
WO-2012138877-A1 N1- AND N2-CARBAMOYL-1,2,3-TRIAZOLE SERINE HYDROLASE INHIBITORS AND METHODS THE SCRIPPS RESEARCH INSTITUTE (US) 2012-10-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140018318-A1 N1- and N2-CARBAMOYL-1,2,3-TRIAZOLE SERINE HYDROLASE INHIBITORS AND METHODS PRSS1, PRSS3, CES1 DAGLA 2511/4885ABHD6 1961/4885DAGLB 2421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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