Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.45 |
| ▸ | PRKDC | P78527 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13194610 | 0.92 | TNKS (0.46) | MTNR1AMTNR1BTP53PIK3CAPRKDC | |
| SCHEMBL13195113 | 0.92 | TP53 (0.56) | MTNR1AMTNR1BSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL13195114 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BTP53ALDH1A1MAPT | |
| SCHEMBL13194513 | 0.88 | PIK3CA (0.47) | MTNR1AMTNR1BPIK3CAPRKDC | |
| SCHEMBL13195116 | 0.88 | RAB9A (0.52) | SMN1; SMN2TP53HTTALDH1A1HPGD | |
| SCHEMBL13195118 | 0.87 | TDP1 (0.42) | MTNR1AMTNR1BSMN1; SMN2TP53HTT | |
| SCHEMBL13195122 | 0.87 | PIK3CA (0.45) | MTNR1AMTNR1BSMN1; SMN2HPGDPIK3CA | |
| SCHEMBL13194535 | 0.87 | PIK3CA (0.45) | MTNR1AMTNR1BSMN1; SMN2HPGDPIK3CA | |
| SCHEMBL15399322 | 0.86 | F10 (0.54) | — | |
| SCHEMBL13194534 | 0.86 | F10 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012136492-A1 | WNT PATHWAY ANTAGONISTS | SIENA BIOTECH S.P.A. (IT) | 2012-10-11 | — | — | WO | disclosed |