Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13195398 | 0.86 | S1PR1 (0.54) | MAOBALOX5NR4A2NR4A1NR4A3 | |
| SCHEMBL13195438 | 0.85 | S1PR1 (0.53) | MAOBALOX5NR4A2NR4A1NR4A3 | |
| SCHEMBL29592445 | 0.85 | MAOB (0.49) | MAOBALOX5S1PR1S1PR5MAOA | |
| SCHEMBL2174555 | 0.84 | L3MBTL1 (0.54) | MAOBGAARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL14970599 | 0.82 | MAOB (0.55) | MAOBNR4A2MAOA | |
| SCHEMBL16410202 | 0.80 | MTNR1A (0.48) | PTGS1GAAMAPTSMN1; SMN2MTNR1A | |
| SCHEMBL20526908 | 0.80 | MAOB (0.56) | MAOBPARP10ALOX5PTGS1PTGS2 | |
| SCHEMBL21455761 | 0.77 | MTNR1A (0.59) | GAARAB9ASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL1819738 | 0.77 | PTGER1 (0.50) | MAPTSMN1; SMN2L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL15876023 | 0.76 | S1PR1 (0.51) | MAOBLTA4HS1PR1S1PR5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012138845-A1 | SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2012-10-11 | — | — | WO | disclosed |