SCHEMBL131960

SCHEMBL131960

CCC1(C(OC(=O)c2cccc(C(=O)O)c2)C2(CC)COC2)COC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.39
TP53 P04637 1/20 0.39
PKM P14618 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
CREBBP Q92793 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 1/20 0.36
KDM6B O15054 1/20 0.36
KDM5C P41229 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
KDM3A Q9Y4C1 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 2/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132923 0.87 MAPT (0.42) KMT2ASMN1; SMN2TP53L3MBTL1NPC1
SCHEMBL16115254 0.84 KMT2A (0.37) KMT2ASMN1; SMN2TP53PKMNFKB1
SCHEMBL2289273 0.83 CA12 (0.39) KMT2ASMN1; SMN2L3MBTL1KDM4ENPC1
SCHEMBL27942852 0.75 TSHR (0.51) KMT2AL3MBTL1CYP2C9HSD17B10
SCHEMBL7181546 0.73 PRKCA (0.48) KMT2ASMN1; SMN2TP53PKMNFKB1
SCHEMBL21459247 0.72
SCHEMBL27980364 0.72 CYP2C9 (0.39) KMT2AL3MBTL1NPC1RAB9ACYP2C9
SCHEMBL3711959 0.72 KMT2A (0.46) KMT2ASMN1; SMN2TP53PKMNFKB1
SCHEMBL9989638 0.72 KMT2A (0.46) KMT2ASMN1; SMN2TP53PKMNFKB1
SCHEMBL28477026 0.72 MAPT (0.39) KMT2ASMN1; SMN2L3MBTL1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1486536-B2 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-10-10 EP disclosed
EP-1452567-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-03-07 EP disclosed
EP-1466946-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2011-11-09 EP disclosed
US-7498375-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2009-03-03 US disclosed
US-7205346-B2 halogen-free, fireproof mixture of thermoplastic resins, containing phosphorus compounds, aromatic resins, nitrogen compounds, metal compounds, stabilizer agents and water repellants POLYPLASTICS CO., LTD. (JP) 2007-04-17 US disclosed
EP-1486536-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2007-01-24 EP disclosed
US-7115677-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-10-03 US disclosed
US-20050004292-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2005-01-06 US disclosed
US-20040266916-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-30 US disclosed
US-20040254270-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-16 US disclosed
EP-1486536-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-12-15 EP disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 EP disclosed
EP-1452567-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-09-01 EP disclosed