SCHEMBL1319629

SCHEMBL1319629

Brc1ccccc1-n1cccc1/C=C/C1OCCO1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1319630 1.00 GAA (0.32) GAA
SCHEMBL12120940 0.80 ATM (0.49) GAA
SCHEMBL1321754 0.78 KMT2A (0.46) GAA
SCHEMBL1319894 0.72 GAA (0.42) GAA
SCHEMBL1319896 0.72 GAA (0.42) GAA
SCHEMBL1321565 0.71 GAA (0.58) GAA
SCHEMBL12473973 0.65 GRIN2D (0.49) GAA
SCHEMBL3257590 0.63 KDM1A (0.48) —
SCHEMBL3503959 0.63 KDM1A (0.48) —
SCHEMBL6983785 0.58 NPC1 (0.54) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348016-B1 Phenyl pyrrole aminoguanidine derivatives SYNACT PHARMA APS (DK) 2016-02-17 — — EP disclosed
EP-2348016-B1 Phenyl pyrrole aminoguanidine derivatives SYNACT PHARMA APS (DK) 2016-02-17 — — EP disclosed
US-8058306-B2 Phenyl pyrrole aminoguanidine derivatives ACTION PHARMA A/S (DK) 2011-11-15 — — US disclosed
US-8058306-B2 Phenyl pyrrole aminoguanidine derivatives ACTION PHARMA A/S (DK) 2011-11-15 — — US disclosed
EP-2348016-A1 Phenyl pyrrole aminoguanidine derivatives Action Pharma A/S (DK) 2011-07-27 — — EP disclosed
EP-2348016-A1 Phenyl pyrrole aminoguanidine derivatives Action Pharma A/S (DK) 2011-07-27 — — EP disclosed
EP-2035373-B1 PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES ACTION PHARMA AS (DK) 2011-05-04 — — EP disclosed
EP-2035373-B1 PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES ACTION PHARMA AS (DK) 2011-05-04 — — EP disclosed
US-20110082183-A1 PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES ACTION PHARMA A/S (DK) 2011-04-07 — — US disclosed
US-20110082183-A1 PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES ACTION PHARMA A/S (DK) 2011-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110082183-A1 PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES MC1R, MC5R, MC4R GAA 1373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback