Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609231 | 0.91 | MAPT (0.43) | ALDH1A1LMNATP53CYP1A2BRCA1 | |
| SCHEMBL13206931 | 0.89 | MTNR1A (0.49) | ALDH1A1LMNATP53CYP1A2BRCA1 | |
| SCHEMBL13198026 | 0.88 | CYP3A4 (0.49) | ALDH1A1LMNATP53CYP1A2BRCA1 | |
| SCHEMBL13198050 | 0.84 | IAPP (0.44) | ALDH1A1SMN1; SMN2TDP1MAPTMEN1 | |
| SCHEMBL9609237 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNATP53CYP1A2BRCA1 | |
| SCHEMBL9609207 | 0.83 | HSD17B10 (0.45) | ALDH1A1LMNATP53CYP1A2BRCA1 | |
| SCHEMBL13206982 | 0.82 | TDP1 (0.44) | ALDH1A1LMNATP53CYP1A2BRCA1 | |
| SCHEMBL13198049 | 0.81 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPTMEN1PKM | |
| SCHEMBL9609219 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNATDP1CASP3SENP8 | |
| SCHEMBL426021 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNATP53CYP1A2BRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776568-B2 | Rhodamine dye compounds for patterns with DNA sequences for kits | APPLIED BIOSYSTEMS, LLC (US) | 2010-08-17 | — | — | US | disclosed |