SCHEMBL1319862

SCHEMBL1319862

CCCCCCCCn1c(N)cc(=O)[nH]c1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
GPR84 Q9NQS5 7/20 0.50
HPGD P15428 3/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
MEN1 O00255 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
USP2 O75604 2/20 0.46
POLB P06746 2/20 0.46
MAPT P10636 2/20 0.46
HTT P42858 1/20 0.46
PKM P14618 1/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
UNG P13051 3/20 0.45
ATM Q13315 1/20 0.45
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4809763 1.00 KMT2A (0.55) KMT2AL3MBTL1GPR84HPGDALDH1A1
SCHEMBL7179000 1.00 KMT2A (0.55) KMT2AL3MBTL1GPR84HPGDALDH1A1
SCHEMBL1713239 0.98 KMT2A (0.56) KMT2AL3MBTL1GPR84HPGDALDH1A1
SCHEMBL1945172 0.93 KMT2A (0.58) KMT2AL3MBTL1GPR84HPGDALDH1A1
SCHEMBL7177762 0.92 KMT2A (0.48) KMT2AL3MBTL1GPR84HPGDALDH1A1
SCHEMBL7177750 0.92 KMT2A (0.48) KMT2AL3MBTL1GPR84HPGDALDH1A1
SCHEMBL1946240 0.86 KMT2A (0.61) KMT2AL3MBTL1GPR84HPGDALDH1A1
SCHEMBL7187029 0.84 MTNR1A (0.56) KMT2AL3MBTL1GPR84HPGDALDH1A1
SCHEMBL7188435 0.84 MTNR1A (0.56) KMT2AL3MBTL1GPR84HPGDALDH1A1
SCHEMBL562714 0.83 MTNR1A (0.57) KMT2AL3MBTL1GPR84HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2792707-B1 Stabiliser systems for polymers containing halogens IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO KG (DE) 2018-06-06 EP disclosed
EP-2110405-B1 STABILISER SYSTEMS FOR POLYMERS CONTAINING HALOGEN IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO KG (DE) 2015-09-02 EP disclosed
EP-2792707-A2 Stabiliser systems for polymers containing halogens IKA Innovative Kunststoffaufbereitung Gmbh & Co.Kg (DE) 2014-10-22 EP disclosed
US-20110275747-A1 STABILIZER SYSTEMS FOR POLYMERS CONTAINING HALOGEN IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO. KG (DE) 2011-11-10 US disclosed
EP-2110405-A1 Stabiliser systems for polymers containing halogen IKA Innovative Kunststoffaufbereitung Gmbh & Co.Kg (DE) 2009-10-21 EP disclosed