Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187029 | 1.00 | MTNR1A (0.56) | MTNR1AMTNR1BGAAMAPK1MAPK10 | |
| SCHEMBL562714 | 0.98 | MTNR1A (0.57) | MTNR1AMTNR1BGAAMAPK1MAPK10 | |
| SCHEMBL1319862 | 0.84 | KMT2A (0.55) | MTNR1AMTNR1BMAPK10GPR84HTT | |
| SCHEMBL4809763 | 0.84 | KMT2A (0.55) | MTNR1AMTNR1BMAPK10GPR84HTT | |
| SCHEMBL7179000 | 0.84 | KMT2A (0.55) | MTNR1AMTNR1BMAPK10GPR84HTT | |
| SCHEMBL9379061 | 0.83 | MAPK10 (0.50) | GAAMAPK10GPR84HTTALDH1A1 | |
| SCHEMBL1713239 | 0.83 | KMT2A (0.56) | MTNR1AMTNR1BGAAGPR84HTT | |
| SCHEMBL1960768 | 0.81 | GAA (0.56) | MTNR1AMTNR1BGAAMAPK1HTT | |
| SCHEMBL1945172 | 0.78 | KMT2A (0.58) | MTNR1AMTNR1BGAAGPR84HPGD | |
| SCHEMBL1959222 | 0.77 | GAA (0.53) | MTNR1AMTNR1BGAAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318168-A1 | Stabiliser combinations for chlorinated polymers | Crompton Vinyl Additives GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |