Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885185 | 0.97 | ALDH1A1 (0.40) | ALDH1A1MAPK1MEN1POLBKMT2A | |
| SCHEMBL10096650 | 0.91 | PDGFRB (0.38) | ALDH1A1MAPK1MEN1POLBKMT2A | |
| SCHEMBL10096264 | 0.90 | MEN1 (0.38) | ALDH1A1MAPK1MEN1POLBKMT2A | |
| SCHEMBL13198730 | 0.90 | PDGFRB (0.41) | ALDH1A1MAPK1MEN1POLBKMT2A | |
| SCHEMBL10096681 | 0.89 | PDGFRB (0.39) | ALDH1A1MAPK1MEN1POLBKMT2A | |
| SCHEMBL10096261 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPK1MEN1POLBKMT2A | |
| SCHEMBL10096412 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPK1MEN1POLBKMT2A | |
| SCHEMBL13198734 | 0.89 | PDGFRB (0.41) | ALDH1A1MAPK1MEN1POLBKMT2A | |
| SCHEMBL2878945 | 0.88 | EGLN2 (0.37) | ALDH1A1MAPK1MEN1POLBKMT2A | |
| SCHEMBL10096363 | 0.88 | MTNR1B (0.42) | ALDH1A1MAPK1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772271-B2 | Methods for treating hepatitis C | PTC THERAPEUTICS, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-7772271-B2 | Methods for treating hepatitis C | PTC THERAPEUTICS, INC. (US) | 2010-08-10 | — | — | US | disclosed |