Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909822 | 0.86 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL4196703 | 0.83 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL16309298 | 0.83 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL4916318 | 0.83 | TSHR (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9312196 | 0.82 | THRB (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL1326895 | 0.81 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9806275 | 0.81 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL4916636 | 0.81 | TSHR (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15249367 | 0.81 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL22709492 | 0.81 | ALDH1A1 (0.48) | TSHRALDH1A1HTTCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2221348-A2 | Pigment dispersion composition, colored curable composition, color filter, liquid crystal display device and solid-state image sensor | FUJIFILM Corporation (JP) | 2010-08-25 | — | — | EP | disclosed |