SCHEMBL13199169

SCHEMBL13199169

Cc1c(C(F)(F)F)ccc(C(F)(F)F)c1C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AR P10275 7/20 0.38
HSD11B1 P28845 1/20 0.37
TAS2R14 Q9NYV8 1/20 0.36
NOTUM Q6P988 1/20 0.35
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35
CES2 O00748 1/20 0.34
KIF11 P52732 5/20 0.33
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
PDE2A O00408 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10800866 0.89 AR (0.33) ARHSD11B1TAS2R14NOTUMTSHR
SCHEMBL19585261 0.87 KIF11 (0.36) ARHSD11B1TAS2R14KIF11CYP11B1
SCHEMBL28194213 0.87 AR (0.32) ARHSD11B1TAS2R14NOTUMPOLB
SCHEMBL2878061 0.84 NOTUM (0.38) ARHSD11B1TAS2R14NOTUMCYP11B1
SCHEMBL10744879 0.84 TAS2R14 (0.34) ARHSD11B1TAS2R14NOTUMCES2
SCHEMBL25012683 0.83 AR (0.43) ARHSD11B1TAS2R14NOTUMCES2
SCHEMBL6630838 0.81 TAS2R14 (0.46) HSD11B1TAS2R14NOTUMPOLBKIF11
SCHEMBL17947171 0.81 PDE2A (0.39) ARNOTUMPDE2A
SCHEMBL13105763 0.81 TAS2R14 (0.39) ARTAS2R14POLBGAATSHR
SCHEMBL13199206 0.79 AR (0.41) ARHSD11B1TAS2R14PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647218-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-05-09 US disclosed
US-20150129849-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-05-14 US disclosed
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 US disclosed
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 US disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed
WO-2010095678-A1 FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM セントラル硝子株式会社 (JP) 2010-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom MCCC2, AFF2, F13A1 AR 4258/4885HSD11B1 4548/4885TAS2R14 873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.