Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 2/20 | 0.30 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15241694 | 0.84 | ELANE (0.37) | ELANEESR1ESR2PPARAPPARD | |
| SCHEMBL14701784 | 0.84 | ELANE (0.42) | ELANEESR1ESR2PPARAPPARD | |
| SCHEMBL16504154 | 0.81 | ELANE (0.32) | ELANEPPARAPPARDPPARG | |
| SCHEMBL13631983 | 0.78 | ELANE (0.43) | ELANEESR1ESR2PPARAPPARD | |
| SCHEMBL14211088 | 0.76 | MAPT (0.57) | ELANECYP1A2 | |
| SCHEMBL16504152 | 0.76 | ELANE (0.45) | ELANEEPHX2NR1H4TRPV1 | |
| SCHEMBL13801167 | 0.74 | ELANE (0.53) | ELANEPRTN3 | |
| SCHEMBL807094 | 0.73 | ELANE (0.46) | ELANEPPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL16504161 | 0.73 | PTPN5 (0.38) | ELANEESR1ESR2NR1H4CYP3A4 | |
| SCHEMBL13199223 | 0.73 | NPC1 (0.31) | ELANEBCHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010095678-A1 | FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM | セントラル硝子株式会社 (JP) | 2010-08-26 | — | — | WO | disclosed |