SCHEMBL16504152

SCHEMBL16504152

CCCC(C)(C)C(=O)C(F)(F)c1ccc(C(F)(F)C(=O)Oc2ccc(C(C)(C)c3ccc(OC(C)(C)CC)cc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.45
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
EPHX2 P34913 1/20 0.31
NR1H4 Q96RI1 1/20 0.31
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16504162 0.88 ELANE (0.49) ELANE
SCHEMBL16504170 0.84 ESR1 (0.36) ELANE
SCHEMBL13199224 0.84 ELANE (0.39) ELANE
SCHEMBL16504159 0.83 PDE2A (0.33) ELANE
SCHEMBL807094 0.80 ELANE (0.46) ELANE
SCHEMBL13801167 0.79 ELANE (0.53) ELANE
SCHEMBL13986205 0.78 ELANE (0.58) ELANE
SCHEMBL16504154 0.78 ELANE (0.32) ELANE
SCHEMBL13199355 0.76 ELANE (0.33) ELANEEPHX2NR1H4TRPV1
SCHEMBL14533677 0.75 LMNA (0.44) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2395040-A1 FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM Central Glass Company, Limited (JP) 2011-12-14 EP disclosed