Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504170 | 0.93 | ESR1 (0.36) | ELANEPPARGPPARDPPARANPC1 | |
| SCHEMBL13199224 | 0.86 | ELANE (0.39) | ELANENPC1POLBCYP2C9RAB9A | |
| SCHEMBL13199223 | 0.84 | NPC1 (0.31) | ELANENPC1POLBCYP2C9RAB9A | |
| SCHEMBL14701784 | 0.83 | ELANE (0.42) | ELANEPPARDPPARA | |
| SCHEMBL16504159 | 0.82 | PDE2A (0.33) | ELANENPC1RAB9A | |
| SCHEMBL13199355 | 0.81 | ELANE (0.33) | ELANEPPARGPPARDPPARA | |
| SCHEMBL16504161 | 0.79 | PTPN5 (0.38) | ELANENPC1POLBRAB9A | |
| SCHEMBL15241694 | 0.79 | ELANE (0.37) | ELANEPPARDPPARA | |
| SCHEMBL16504152 | 0.78 | ELANE (0.45) | ELANE | |
| SCHEMBL15957712 | 0.74 | MAOB (0.39) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395040-A1 | FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM | Central Glass Company, Limited (JP) | 2011-12-14 | — | — | EP | disclosed |