Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 4/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199561 | 0.91 | ABCB1 (0.45) | KCNE1KCNQ1ABCB1KCNA5 | |
| SCHEMBL13199626 | 0.88 | KCNE1 (0.39) | KCNE1KCNQ1ABCB1KDM1AHDAC8 | |
| SCHEMBL2883691 | 0.88 | KCNE1 (0.40) | KCNE1KCNQ1ABCB1GRM2KCNA5 | |
| SCHEMBL2883686 | 0.88 | KCNE1 (0.40) | KCNE1KCNQ1ABCB1GRM2KCNA5 | |
| SCHEMBL13199632 | 0.87 | NR1D1 (0.36) | KCNE1KCNQ1ABCB1 | |
| SCHEMBL13199622 | 0.79 | ABCB1 (0.44) | KCNE1KCNQ1ABCB1KCNA5 | |
| SCHEMBL12580755 | 0.79 | GRM2 (0.36) | KCNE1KCNQ1ABCB1GRM2 | |
| SCHEMBL13199624 | 0.78 | ABCB1 (0.44) | KCNE1KCNQ1ABCB1KCNA5 | |
| SCHEMBL13199558 | 0.78 | ABCB1 (0.43) | KCNE1KCNQ1ABCB1KCNA5 | |
| SCHEMBL13515331 | 0.77 | ABCB1 (0.35) | KCNE1KCNQ1ABCB1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718629-B1 | Benzopyran compounds useful for the treatment of arrhytmia | NISSAN CHEMICAL IND LTD (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-7781483-B2 | Benzopyran compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-7781483-B2 | Benzopyran compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-24 | — | — | US | disclosed |