Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13196692 | 1.00 | MEN1 (0.39) | MEN1KMT2AGPR119NR1I2GRM5 | |
| SCHEMBL2800961 | 0.84 | BRD4 (0.40) | BRD4 | |
| SCHEMBL13200462 | 0.80 | TACR1 (0.43) | MEN1KMT2A | |
| SCHEMBL13196674 | 0.80 | TACR1 (0.43) | MEN1KMT2A | |
| SCHEMBL15185026 | 0.79 | HCRTR2 (0.42) | MEN1KMT2AGPR119GRM5KDM4E | |
| SCHEMBL15215454 | 0.74 | LMNA (0.43) | MEN1KMT2AGPR119NR1I2LMNA | |
| SCHEMBL13200870 | 0.73 | CCR5 (0.38) | GPR119NR1I2TERT | |
| SCHEMBL13196711 | 0.73 | CCR5 (0.38) | GPR119NR1I2TERT | |
| SCHEMBL15185074 | 0.73 | GRM5 (0.41) | MEN1KMT2AGPR119GRM5KDM4E | |
| SCHEMBL20170496 | 0.73 | HSP90AA1 (0.56) | MEN1KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197724-A1 | 6.5 -PYRROLOPIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS | BAO JIANMING | 2010-08-05 | — | — | US | disclosed |
| WO-2009002770-A1 | 6.5-PYRROLOPIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197724-A1 | 6.5 -PYRROLOPIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS | TACR1, TACR2, HTR1D | MEN1 1012/4885KMT2A 303/4885GPR119 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.