Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14593806 | 1.00 | ALDH1A1 (0.32) | ALDH1A1GAAMAPTHDAC8POLB | |
| SCHEMBL13069360 | 0.93 | MAPT (0.34) | ALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL14566058 | 0.90 | ALDH1A1 (0.33) | ALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL19348870 | 0.90 | HDAC8 (0.32) | ALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL17784551 | 0.90 | ALDH1A1 (0.33) | ALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL14435452 | 0.90 | ALDH1A1 (0.33) | ALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL17784639 | 0.90 | HDAC8 (0.32) | ALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL14559246 | 0.90 | ABL1 (0.36) | MAPT | |
| Bromide SCHEMBL19348863 | 0.89 | ALDH1A1 (0.32) | ALDH1A1MAPTHDAC8 | |
| SCHEMBL17784676 | 0.89 | PRSS1 (0.32) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7771490-B2 | Dyes containing a thiol group | CIBA CORPORATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-20090300857-A1 | hair dyes; washfast; thioethylation | CIBA CORPORATION (US) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090300857-A1 | hair dyes; washfast; thioethylation | TMT1A, WASHC4, TPH1 | ALDH1A1 13/4885GAA 4789/4885MAPT 4209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.