Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 11/20 | 0.68 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13218281 | 1.00 | VDR (0.68) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL9009928 | 0.94 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL9010345 | 0.94 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL10820222 | 0.94 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL23752370 | 0.94 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL23752369 | 0.94 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL13666147 | 0.94 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL859793 | 0.94 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL9009884 | 0.94 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL798548 | 0.94 | VDR (0.76) | VDRCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41491-E1 | for suppression of secondary hyperparathyroidism of renal osteodystrophy; treats autoimmune diseases, including multiple sclerosis, lupis, diabetes mellitus, host versus graft reaction, and rejection of organ transplants; antiinflammtory and anticarcinogenic agent | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-RE41474-E1 | (20S)-1α-Hydroxy-2-Methylene-19-Nor-Bishomopregnacalciferol and its uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-08-03 | — | — | US | disclosed |