Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13218257 | 0.83 | MAPT (0.65) | GRM5ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3640449 | 0.81 | GRM5 (0.70) | GRM5ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL12124637 | 0.81 | GRM5 (0.62) | GRM5ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL12124656 | 0.78 | GRM5 (0.67) | GRM5ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3644034 | 0.78 | GRM5 (0.66) | GRM5ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL4701230 | 0.78 | ALDH1A1 (0.66) | GRM5ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL12124661 | 0.76 | GRM5 (0.63) | GRM5ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3639130 | 0.74 | GRM5 (0.70) | GRM5ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL4696957 | 0.73 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL3644509 | 0.73 | GRM5 (0.67) | GRM5ALDH1A1MAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767699-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA, L.P. (US) | 2010-08-03 | — | — | US | disclosed |